Bobcat339 [CAS 2280037-51-4]

Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1].

[2280037-51-4]

C16H12ClN3O

297.74

NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O

DNA Methyltransferase; TET Protein

TET1; TET2

99.44

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335