Boc-gly-PEG3-endo-BCN [CAS 2110444-63-6]
Boc-gly-PEG3-endo-BCN [CAS 2110444-63-6]
SKU:QM-0064011
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Product Details
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Description
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2]. Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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CAS Number
[2110444-63-6]
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Molecular Formula
C28H47N3O8
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Molecular Weight
553.69
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Smiles
O=C(OC(C)(C)C)NCC(NCCCOCCOCCOCCCNC(OCC1C2CCC#CCCC12)=O)=O
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Target
ADC Linker; PROTAC Linkers
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Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Boc-gly-PEG3-endo-BCN [CAS 2110444-63-6]
Boc-gly-PEG3-endo-BCN is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.