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Bohemine [CAS 189232-42-6]

Bohemine [CAS 189232-42-6]

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SKU:QM-0142394-01

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  • Description

    Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 μM, 83 μM, and 2.7 μM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 μM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities[1][2].

  • CAS Number

    [189232-42-6]

  • Molecular Formula

    C18H24N6O

  • Molecular Weight

    340.42

  • Smiles

    OCCCNC1=NC(NCC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1

  • Target

    CDK; ERK

  • Isoform

    CDK2; CDK9; ERK2

  • Purity

    98.93

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302-H315-H319-H332-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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5 mgQM-0142394-01
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10 mM - 1 mLQM-0142394-02
10 mM - 1 mLQM-0142394-02
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10 mgQM-0142394-03
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50 mgQM-0142394-04
50 mgQM-0142394-04
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100 mgQM-0142394-05
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Bohemine [CAS 189232-42-6]

Bohemine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.