Bonducellin [CAS 83162-84-9]

Bonducellin is a a homoisoflavonoid, which can be isolated from Caesalpinia digyna roots. Bonducellin is a potent inhibitor of efflux pump (EP), while EP induces resistance in mycobacteria and serves as a target of anti-TB (tuberculosis) agents. Bonducellin reduces MIC of EtBr by 8-fold against M. smegmatis (MIC=62.5 mg/L) [1].

[83162-84-9]

C17H14O4

282.29

O=C1/C(COC2=CC(O)=CC=C12)=C/C3=CC=C(OC)C=C3

Bacterial

10 mM in DMSO

Room temperature