BRD-4592 [CAS 2119598-24-0]

BRD-4592 is an allosteric inhibitor targeting Mycobacterium tuberculosis tryptophan synthase (TrpAB) . BRD-4592 binds at the α-β-subunit interface of TrpAB, with an IC50 of 70.9 nM for the α-subunit and 22.6 nM for the β-subunit[1].

[2119598-24-0]

C17H15FN2O

282.31

N#C[C@H]1[C@H](C2=CC=C(C3=C(C=CC=C3)F)C=C2)[C@@H](N1)CO

Bacterial

Room temperature