BRD-SF2 [CAS 3050690-26-8]

BRD-SF2 is a BRD4-targeted PROTAC degrader (DC50: 17.2 μM) (Blue: VHL ligand, black: linker, pink: BRD4 ligand) [1].

[3050690-26-8]

C59H76FN9O13S2

1202.42

O=C1N(C)C=C(C2=NC(C=C(C3CCN(C(COCCOCCOCCNC(C[C@H](NC([C@H]4N(C([C@@H](C5=CC(C)=NO5)C(C)C)=O)C[C@H](S(=O)(F)=O)C4)=O)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)CC3)C=C8)=C8N2C(COC)COC)C=C1C

Epigenetic Reader Domain; PROTACs

BRD4

10 mM in DMSO

Room temperature