Bremazocine [CAS 75684-07-0]

Bremazocine is a potent opioid kappa receptor agonist with analgesic activity. Bremazocine induces peripheral analgesia by releasing endogenous norepinephrine. The analgesic effect of bremazocine is associated with interaction with adenosine receptors. Bremazocine produces a dose-dependent peripheral analgesia after topical application. The effect of bremazocine is affected by nonselective α (2) adrenaline receptor antagonists, suggesting that it acts through a norepinephrine pathway[1].

[75684-07-0]

C20H29NO2

315.45

CC[C@]1(CCN2CC3(CC3)O)C4=CC(O)=CC=C4C[C@]2([H])C(C)1C

Adrenergic Receptor

Room temperature