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Brepocitinib [CAS 1883299-62-4]

Brepocitinib [CAS 1883299-62-4]

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SKU:QM-0137656-01

£118.38 GBP
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  • Description

    Brepocitinib (PF-06700841) is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively[1].

  • CAS Number

    [1883299-62-4]

  • Molecular Formula

    C18H21F2N7O

  • Molecular Weight

    389.4

  • Smiles

    O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3

  • Target

    JAK

  • Isoform

    JAK1; JAK2; JAK3

  • Purity

    99.97

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H303, H315, H319, H335

  • Precautions

    H303, H315, H319, H335

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5 mgQM-0137656-01
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10 mM - 1 mLQM-0137656-02
10 mM - 1 mLQM-0137656-02
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10 mgQM-0137656-03
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50 mgQM-0137656-04
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100 mgQM-0137656-05
100 mgQM-0137656-05
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Brepocitinib [CAS 1883299-62-4]

Brepocitinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.