Britannilactone diacetate [CAS 1286694-67-4]

Britannilactone diacetate (1,6-O, O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property[1].

[1286694-67-4]

C19H26O6

350.41

O=C1O[C@@]2([H])[C@@]([C@H](OC(C)=O)C([C@@H](C)CCCOC(C)=O)=C(C)C2)([H])C1=C

NO Synthase

10 mM in DMSO

Room temperature