Bromotetrandrine [CAS 62067-29-2]
Bromotetrandrine [CAS 62067-29-2]
SKU:QM-0004720
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Product Details
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Description
Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp) -mediated multidrug resistance (MDR) . Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment[1][2].
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CAS Number
[62067-29-2]
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Molecular Formula
C38H41BrN2O6
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Molecular Weight
701.65
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Smiles
COC1=C2C3=C(CCN([C@@]3([H])CC4=CC=C(OC)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CCN6C)OC)C=C5)=C4)C)C(Br)=C1OC
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Target
Drug Derivative; P-glycoprotein
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Shipping Conditions
Room temperature
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Bromotetrandrine [CAS 62067-29-2]
Bromotetrandrine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.