Name: BSJ-03-204 [CAS 2349356-09-6]
Brand: QuantiMol
SKU: QM-0145435-01
Price: 226.18 GBP
Availability: InStock

Product Details

Description
BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity[1].
CAS Number
[2349356-09-6]
Molecular Formula
C43H48N10O8
Molecular Weight
832.9
Smiles
O=C1N(C2CCCC2)C3=NC(NC4=CC=C(N(CC5)CCN5CCCCNC(COC6=C(C(N7C(CCC8=O)C(N8)=O)=O)C(C7=O)=CC=C6)=O)C=N4)=NC=C3C(C)=C1C(C)=O
Target
CDK; PROTACs
Isoform
CDK4; CDK6
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C (Powder, protect from light)
Shipping Conditions
Blue Ice

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0145435-01	1 mgQM-0145435-01 £226.18/ea	£0.00	Quantity	£226.18/ea	£0.00

5 mgQM-0145435-02	5 mgQM-0145435-02 £489.83/ea	£0.00	Quantity	£489.83/ea	£0.00

10 mM - 1 mLQM-0145435-03	10 mM - 1 mLQM-0145435-03 £717.03/ea	£0.00	Quantity	£717.03/ea	£0.00

10 mgQM-0145435-04	10 mgQM-0145435-04 £777.78/ea	£0.00	Quantity	£777.78/ea	£0.00

25 mgQM-0145435-05	25 mgQM-0145435-05 £1,430.24/ea	£0.00	Quantity	£1,430.24/ea	£0.00

50 mgQM-0145435-06	50 mgQM-0145435-06 £2,183.54/ea	£0.00	Quantity	£2,183.54/ea	£0.00

100 mgQM-0145435-07	100 mgQM-0145435-07 £3,188.34/ea	£0.00	Quantity	£3,188.34/ea	£0.00

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BSJ-03-204 [CAS 2349356-09-6]

BSJ-03-204 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.