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BT2 [CAS 34576-94-8]

BT2 [CAS 34576-94-8]

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QM-0138552-01

£60.19 GBP
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Product Details

  • Description

    BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC) [1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2].

  • CAS Number

    [34576-94-8]

  • Molecular Formula

    C9H4Cl2O2S

  • Molecular Weight

    247.1

  • Smiles

    O=C(O)C1=C(C2=CC=C(C=C2S1)Cl)Cl

  • Target

    Bcl-2 Family

  • Isoform

    Mcl-1

  • Concentration

    10mM

  • Purity

    99.85

  • Solubility

    DMSO : 62.5 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H315, H319, H335

  • Precautions

    H315, H319, H335
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Variant Variant total Quantity Price Variant total
10 mM - 1 mLQM-0138552-01
10 mM - 1 mLQM-0138552-01
£60.19/ea		 £0.00
£60.19/ea £0.00
10 mgQM-0138552-02
10 mgQM-0138552-02
£78.82/ea		 £0.00
£78.82/ea £0.00
25 mgQM-0138552-03
25 mgQM-0138552-03
£111.63/ea		 £0.00
£111.63/ea £0.00
50 mgQM-0138552-04
50 mgQM-0138552-04
£129.63/ea		 £0.00
£129.63/ea £0.00
100 mgQM-0138552-05
100 mgQM-0138552-05
£232.25/ea		 £0.00
£232.25/ea £0.00
500 mgQM-0138552-06
500 mgQM-0138552-06
£501.98/ea		 £0.00
£501.98/ea £0.00
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BT2 [CAS 34576-94-8]

BT2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.