BTK-IN-11 [CAS 2765852-46-6]

BTK-IN-11 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-11 has the potential for the research of related diseases, especially autoimmune diseases, inflammatory diseases or cancer (extracted from patent WO2022063101A1, compound Z2) [1].

[2765852-46-6]

C26H22ClN5O3

487.94

CN1CCC2(NC3=C4C(C(C5=CC=C(C=C5Cl)OC6=CC=CC=C6)=O)=CNC4=NC=C3NC2=O)C1

Btk

10 mM in DMSO

Room temperature