BTK-IN-34 [CAS 3016419-52-3]

BTK-IN-34 (compound 9h) is a selective BTK inhibitor. BTK-IN-34 shows antiproliferative activity in RAMOS cells through selective inhibition of pBTK (Tyr223) without affecting Lyn and Syk, upstream proteins in the BCR signaling pathway[1].

[3016419-52-3]

C22H29N3O4S

431.55

O=C1NC2=C(C=C(S(=O)(N3CCN(C(CCCC)=O)CC3)=O)C=C2)/C1=C4CCCC\4

Btk

10 mM in DMSO

Room temperature