BTK-IN-6 [CAS 2662512-08-3]

BTK-IN-6 is a potent inhibitor of Bruton's Tyrosine Kinase (BTK) . BTK is a member of the Tec family of tyrosine kinases and plays an important role in the regulation of early B-cell development and mature B-cell activation and survival. BTK-IN-6 has the potential for the research of immune disorders, cancer, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders, and neurological disorders (extracted from patent WO2021136219A1, compound 8) [1].

[2662512-08-3]

C23H22FN5O3

435.45

NC1=NC=NN2C([C@H]3CC[C@H](OC3)CO)=NC(C4=C(C=C(C=C4)OC5=CC=CC=C5)F)=C12

Btk

10 mM in DMSO

Room temperature