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BTX-6654 (formate)

BTX-6654 (formate)

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SKU:QM-0008014-01

£803.30 GBP
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  • Description

    BTX-6654 (formate) is a target-dependent and -specific cereblon-based bifunctional SOS1 PROTAC degrader. BTX-6654 (formate) reduces downstream signaling markers pERK and pS6, and displays antiproliferative activity in cells harboring various KRAS mutations[1].

  • Molecular Formula

    C51H59F4N9O7

  • Molecular Weight

    986.06

  • Smiles

    FC(F)(F)C1=C(C)C([C@@H](C)NC2=NN=C(C)C3=CC=C(N4CCN(C(C5CCN(C(CCN6CCC(C7=CC(CN(C8CCC(NC8=O)=O)C9=O)=C9C=C7F)CC6)=O)CC5)=O)CC4)C=C32)=CC=C1.O=CO

  • Target

    ERK; PROTACs; SOS1

  • Purity

    98.85

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
1 mgQM-0008014-01
1 mgQM-0008014-01
£803.30/ea
£0.00
£803.30/ea £0.00
5 mgQM-0008014-02
5 mgQM-0008014-02
£1,933.25/ea
£0.00
£1,933.25/ea £0.00
10 mgQM-0008014-03
10 mgQM-0008014-03
£3,061.99/ea
£0.00
£3,061.99/ea £0.00
25 mgQM-0008014-04
25 mgQM-0008014-04
£5,698.53/ea
£0.00
£5,698.53/ea £0.00

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BTX-6654 (formate)

BTX-6654 (formate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.