BuChE-IN-15

BuChE-IN-15 (compound D12) is a selective BuChE/FAAH dual inhibitor with and show IC50 values of 81 and 400 nM for hBuChE and hFFAH, respectively. BuChE-IN-15 possesses good BBB penetration, and shows neuroprotection.BuChE-IN-15 can be used for study of Alzheimer[1].

C18H18FNO4

331.34

COC1=CC=C(C(C(C)=O)=C1)OC(N(CC2=CC=C(C=C2)F)C)=O

Cholinesterase (ChE) ; FAAH

Room temperature