Budipine [CAS 57982-78-2]

Budipine is an anti-parkinson agent. Budipine also is a substrate of P-glycoprotein (P-gp), is mediated the uptake into the brain by P-gp. Budipine also is N-methyl-d-aspartate (NMDA) antagonist, and has indirect dopaminergic effects through an improved dopamine release, the inhibition of monoamine oxidase type B (MAO-B) . Budipine can be used for the research of CNS disorders include Parkinson disease[1].

[57982-78-2]

C21H27N

293.45

CC(N1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)CC1)(C)C

IGluR

NMDA Receptor

10mM

99.41

DMSO : 25 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335