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Butein [CAS 487-52-5]

Butein [CAS 487-52-5]

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QM-0153844-01

£101.50 GBP
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Product Details

  • Description

    Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4[1]. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells[2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a[3]. Butein is a SIRT1 activator (STAC) .

  • CAS Number

    [487-52-5]

  • Molecular Formula

    C15H12O5

  • Molecular Weight

    272.25

  • Smiles

    OC1=CC=C(C(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=C1

  • Target

    Apoptosis; Autophagy; EGFR; Phosphodiesterase (PDE)

  • Isoform

    EGFR/ErbB1/HER1; PDE4

  • Purity

    99.64

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
2 mgQM-0153844-01
2 mgQM-0153844-01
£101.50/ea		 £0.00
£101.50/ea £0.00
10 mM - 1 mLQM-0153844-02
10 mM - 1 mLQM-0153844-02
£139.75/ea		 £0.00
£139.75/ea £0.00
5 mgQM-0153844-03
5 mgQM-0153844-03
£148.75/ea		 £0.00
£148.75/ea £0.00
10 mgQM-0153844-04
10 mgQM-0153844-04
£248.04/ea		 £0.00
£248.04/ea £0.00
50 mgQM-0153844-05
50 mgQM-0153844-05
£602.83/ea		 £0.00
£602.83/ea £0.00
100 mgQM-0153844-06
100 mgQM-0153844-06
£928.45/ea		 £0.00
£928.45/ea £0.00
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Butein [CAS 487-52-5]

Butein is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.