BVDU 5′-Triphosphate [CAS 77222-61-8]

BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.

[77222-61-8]

C11H16BrN2O14P3

573.08

OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O

DNA/RNA Synthesis; HSV

10 mM in DMSO

Room temperature