C (avb6) -DOTA (TFA)

C (avb6) -DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with DOTA chelator. The Lu (III) complex of c (avb6) -DOTA TFA has a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be used as a tumor diagnostic[1].

C69H102F3N17O20

1546.65

OC(C(F)(F)F)=O.O=C([C@H]1CCCN1C2=O)N([C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CC3=CC=CC=C3)=O)C)=O)CC(C)C)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CC4=CC=CC=C4)=O)CCCCNC(CN5CCN(CCN(CCN(CC5)CC(O)=O)CC(O)=O)CC(O)=O)=O)C

Integrin

96.83

DMSO : 100 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice