C-di-AMP [CAS 54447-84-6]
C-di-AMP [CAS 54447-84-6]
SKU:QM-0140817-01
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Product Details
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Description
C-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses[1][2][3][4].
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CAS Number
[54447-84-6]
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Molecular Formula
C20H24N10O12P2
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Molecular Weight
658.41
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Smiles
O[C@H]([C@@](OP(O)(OC[C@](O[C@@H](N1C2=NC=NC(N)=C2N=C1)[C@@H]3O)([H])[C@@]3([H])O4)=O)([H])[C@](COP4(O)=O)([H])O5)[C@@H]5N6C7=NC=NC(N)=C7N=C6
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Target
Bacterial; Endogenous Metabolite; STING
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Purity
99.29
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Solubility
H2O : 3.33 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319
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Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
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C-di-AMP [CAS 54447-84-6]
C-di-AMP is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.