C-Fms-IN-6 [CAS 1628574-81-1]

C-Fms-IN-6 is a potent inhibitor of c-FMS, with an IC50 of ≤10 nM for unphosphorylated c-FMS, also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50, > 1 μM) . Used in the research of autoimmune diseases[1].

[1628574-81-1]

C22H25N7O2

419.48

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(CC)N=C4)=NC=C3)C=C2)N=C(C(C)(C)C)N1

C-Fms

10 mM in DMSO

Room temperature