C18 LPA [CAS 799279-67-7]

C18 LPA (PA (18:0e/0:0) ) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs) . It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer.

[799279-67-7]

C21H48NO6P

441.58

O[C@H](COCCCCCCCCCCCCCCCCCC)COP(O)(O)=O.N

Calcium Channel; G Protein-coupled Receptor Kinase (GRK)

Room temperature