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SKU:QM-0137650-01
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CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity[1].
[1370032-19-1]
C24H24N2O3
388.46
O=C(/C(CN(C)C/1)=C/C2=CNC3=C2C=CC=C3)C1=C\C4=CC=C(OC)C(OC)=C4
Apoptosis; Atg8/LC3; Autophagy; p62
99.14
DMSO : 77.5 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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CA-5f is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.