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Cadefrecitinib [CAS 2308520-97-8]

Cadefrecitinib [CAS 2308520-97-8]

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QM-0072612-01

£275.99 GBP
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Product Details

  • Description

    Cadefrecitinib (GLPG3667) is a reversible, ATP-competitive and orally active TYK2 inhibitor with an IC50 of 2.3 nM. Cadefrecitinib inhibits IFNα/pSTAT1, and the IC50 values ​​in human peripheral blood mononuclear cell (PBMC) and whole blood assays are 70 nM and 623 nM, respectively. Cadefrecitinib has the potential for the study of inflammatory and autoimmune diseases[1].

  • CAS Number

    [2308520-97-8]

  • Molecular Formula

    C22H21N9O2

  • Molecular Weight

    443.46

  • Smiles

    N#CC1=NC=C(C(C)=C1)OC2=CC(NC3=NN=C(N4CCOCC4)C=C3)=C(N=CN5C)C5=N2

  • Target

    JAK

  • Isoform

    JAK1; JAK2; JAK3; Tyk2

  • Purity

    99.81

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0072612-01
1 mgQM-0072612-01
£275.99/ea		 £0.00
£275.99/ea £0.00
5 mgQM-0072612-02
5 mgQM-0072612-02
£464.31/ea		 £0.00
£464.31/ea £0.00
10 mgQM-0072612-03
10 mgQM-0072612-03
£670.87/ea		 £0.00
£670.87/ea £0.00
25 mgQM-0072612-04
25 mgQM-0072612-04
£1,179.95/ea		 £0.00
£1,179.95/ea £0.00
50 mgQM-0072612-05
50 mgQM-0072612-05
£1,618.57/ea		 £0.00
£1,618.57/ea £0.00
100 mgQM-0072612-06
100 mgQM-0072612-06
£2,121.57/ea		 £0.00
£2,121.57/ea £0.00
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Cadefrecitinib [CAS 2308520-97-8]

Cadefrecitinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.