CALP3 (TFA)

CALP3 TFA, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 TFA can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 TFA has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia[1][2].

C46H69F3N10O11

995.1

O=C([C@@H](N)C(C)C)N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(NCC(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC1=CC=CC=C1)=O)=O)=O)=O)CC2=CC=CC=C2)=O.O=C(O)C(F)(F)F

Calcium Channel

Calcium Channel

10 mM in DMSO

Room temperature