Calpinactam [CAS 1205538-83-5]

Calpinactam (FKI-4905), a fungal metabolite, is a new anti-mycobacterial agent.Calpinactam is active only against Mycobacteria among various microorganisms, including Gram-positive and Gram-negative bacteria, fungi and yeasts. Calpinactam inhibits the growth of Mycobacterium smegmatis and Mycobacterium tuberculosis with MIC values of 0.78 and 12.5 μg/ml, respectively[1].

[1205538-83-5]

C38H57N9O8

767.91

O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC=N1)C(N[C@H](CCC(O)=O)C(N[C@H]([C@@H](C)CC)C(N[C@@H]2C(NCCCC2)=O)=O)=O)=O)=O)[C@@H](CC3=CC=CC=C3)N

Bacterial; Endogenous Metabolite

Microbial Metabolite

10 mM in DMSO

Room temperature

H302+H312+H332

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501