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Camptothecin derivative-3 [CAS 2378619-11-3]
Camptothecin derivative-3 [CAS 2378619-11-3]
SKU:QM-0014426
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Product Details
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Description
Camptothecin derivative-3 (Compound 11) is a derivative of Camptothecin and can serve as a payload for ADCs. Camptothecin derivative-3 has certain cytotoxicity, with IC50 values of 2 nM and 0.9 nM against HSC-2 and Namalwa/luc cells, respectively. Camptothecin derivative-3 can be used in tumor-related research[1].
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CAS Number
[2378619-11-3]
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Molecular Formula
C24H22FN3O6
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Molecular Weight
467.45
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Smiles
CC[C@@]1(O)C2=C(COC1=O)C(N(CC3=C(C4=CC(C)=C(C=C4N=C35)F)CNC(CO)=O)C5=C2)=O
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Target
ADC Payload; Drug Derivative
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Solubility
DMSO : 3.85 mg/mL (ultrasonic; warming; heat to 60°C)
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Shipping Conditions
Room temperature
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Camptothecin derivative-3 [CAS 2378619-11-3]
Camptothecin derivative-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.