Carbenoxolone (disodium) [CAS 7421-40-1]
Carbenoxolone (disodium) [CAS 7421-40-1]
SKU:QM-0159710-01
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Product Details
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Description
Carbenoxolone disodium is the active metabolite of Glycyrrhizic acid and the inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD[1]. Carbenoxolone disodium is an uncoupling agent for gap junctions and a potent inhibitor of Vaccinia virus replication[2]. Carbenoxolone disodium is used for the study of peptic, esophageal and oral ulceration and inflammation. Carbenoxolone disodium inhibits Vaccinia virus replication.
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CAS Number
[7421-40-1]
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Molecular Formula
C34H48Na2O7
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Molecular Weight
614.72
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Smiles
CC(C)([C@]1([H])CC[C@@]([C@@]2(CC[C@]3(CC[C@](C[C@@]3([H])C2=C4)(C)C(O[Na])=O)C)C)5C)[C@@H](OC(CCC(O[Na])=O)=O)CC[C@]1(C)[C@@]5([H])C4=O
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Target
11β-HSD; Gap Junction Protein; Orthopoxvirus
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Purity
99.94
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Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Carbenoxolone (disodium) [CAS 7421-40-1]
Carbenoxolone (disodium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.