Carboxyatractyloside (tripotassium) [CAS 77228-71-8]

Carboxyatractyloside tripotassium is a diterpenoid. Carboxyatractyloside tripotassium can be isolated from plants of the genus Xanthium. Carboxyatractyloside tripotassium is an ADP/ATP carrier inhibitor, inhibiting mitochondrial ADP/ATP transport. Carboxyatractyloside tripotassium promotes ROS production, induces Ca2+ release, and leads to mitochondrial dysfunction. Carboxyatractyloside tripotassium induces lethargy, weakness, and epileptic seizures in rats[1][2][3][4][5][6].

[77228-71-8]

C31H43K3O18S2

885.09

C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])[C@@](C(O)=O)(C(O[K])=O)C[C@@H](O[C@@H]5[C@H]([C@@H]([C@H]([C@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H]

Calcium Channel; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

99.97

H2O : ≥ 50 mg/mL

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice

H301+H311+H331

H301+H311+H331