Cardiogenol C [CAS 671225-39-1]

Cardiogenol C is a potent cell-permeable pyrimidine inducer which prompts the differentiation of ESCs into cardiomyocytes (EC50=100 nM) [1]. Cardiogenol C also acts cardiomyogenic on already lineage-committed progenitor cell types with a limited degree of plasticity. Cardiogenol C is a useful cardiomyogenic agent and can be used as a tool to improve cardiac repair by cell transplantation therapy in animal models[2].

[671225-39-1]

C13H16N4O2

260.29

COC1=CC=C(NC2=NC=CC(NCCO)=N2)C=C1

Wnt; β-catenin

10 mM in DMSO

Room temperature

H302

P264-P270-P330-P501