Carotegrast methyl [CAS 401905-67-7]

Carotegrast methyl (AJM300) is an orally active and selective α4 integrin antagonist. HCA2969, an active metabolite of Carotegrast methyl, is a specific and dual α4β1/α4β7 integrin antagonist. Carotegrast methyl prevents the development of colitis in mice[1].

[401905-67-7]

C28H26Cl2N4O5

569.44

O=C([C@@H](NC(C1=C(C=CC=C1Cl)Cl)=O)CC2=CC=C(C=C2)N3C(N(C4=C(C3=O)C=C(C=C4)N(C)C)C)=O)OC

Integrin

10mM

99.24

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature