Carvedilol-d4 [CAS 1133705-56-2]

Carvedilol-d4 is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].

[1133705-56-2]

C24H22D4N2O4

410.5

COC(C=CC=C1)=C1OC([2H])([2H])C([2H])([2H])NCC(O)COC2=C3C4=CC=CC=C4NC3=CC=C2

Adrenergic Receptor; Autophagy

99.8

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature