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Catadegbrutinib [CAS 2736508-60-2]

Catadegbrutinib [CAS 2736508-60-2]

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QM-0152899-01

£118.38 GBP
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Product Details

  • Description

    BGB-16673 (BGB-16673; BTK-IN-29) is an orally active, selectively chimeric degradation activator compound (CDAC), targeting BTK (IC50=0.69 nM) . BGB-16673 ligates BTK to E3 ubiquitin ligase, causing BTK to undergo polyubiquitination, which is then recognized and degraded by the proteasome, thereby exerting efficient BTK degradation activity. BGB-16673 can be used in the research of B-cell malignancies such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and mantle cell lymphoma[1][2][3].

  • CAS Number

    [2736508-60-2]

  • Molecular Formula

    C47H54N12O4

  • Molecular Weight

    851.01

  • Smiles

    CC1=C([C@@H](C)NC(C2=NC(C(C)(C)C)=NO2)=O)C=CC(C3=C4C(NC(C5=CN=C(N6CCN(CC6)CC7CCN(C8=CC=C(N9C(NC(CC9)=O)=O)C=C8)CC7)C=C5)=C4)=NC=N3)=C1

  • Target

    Btk; PROTACs

  • Purity

    99.18

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light, stored under nitrogen)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0152899-01
1 mgQM-0152899-01
£118.38/ea		 £0.00
£118.38/ea £0.00
5 mgQM-0152899-02
5 mgQM-0152899-02
£288.14/ea		 £0.00
£288.14/ea £0.00
10 mgQM-0152899-03
10 mgQM-0152899-03
£432.73/ea		 £0.00
£432.73/ea £0.00
25 mgQM-0152899-04
25 mgQM-0152899-04
£662.36/ea		 £0.00
£662.36/ea £0.00
50 mgQM-0152899-05
50 mgQM-0152899-05
£916.29/ea		 £0.00
£916.29/ea £0.00
100 mgQM-0152899-06
100 mgQM-0152899-06
£1,267.43/ea		 £0.00
£1,267.43/ea £0.00
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Catadegbrutinib [CAS 2736508-60-2]

Catadegbrutinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.