CAY10512 [CAS 139141-12-1]

CAY10512 is a NF-κB inhibitor. CAY10512 can suppress the upregulation of NF-κB-sensitive proinflammatory miRNAs (miRNA-9, miRNA-125b, miRNA-146a, miRNA-155) in cerebrospinal fluid and extracellular fluid. CAY10512 significantly reduces the release of pro-inflammatory cytokines (such as TNF-α, MCP-1, IL-8, IL-6) . CAY10512 can be used for researchs on neuroinflammation, islet transplantation and microRNA regulation[1][2][3].

[139141-12-1]

C15H13FO

228.26

COC(C=C1)=CC=C1/C=C/C2=C(C=CC=C2)F

Interleukin Related; NF-κB; TNF Receptor

IL-6; IL-8; NF-κB

97

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335