CAY10669 [CAS 1243583-88-1]

CAY10669 (compound 6d) is an anacardic acid derivative that inhibits histone acetyltransferase PCAF with an IC50 of 662 μM[1]. CAY10669 enhances the SAHA-induced acetylation in HEPG2 cells, exhibits cytotoxicity in zebrafish embryo, promotes transgene expression in CHO-K1 cells[1][2][3].

[1243583-88-1]

C20H22O4

326.39

OC1=CC=CC(/C=C\C2=CC=C(C=C2)OCCCCC)=C1C(O)=O

Histone Acetyltransferase

GCN5/PCAF

99.9

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice