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CBI1

CBI1

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QM-0135307

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Product Details

  • Description

    CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex[1].

  • Molecular Formula

    C15H19BrN4OS2

  • Molecular Weight

    415.37

  • Smiles

    BrC1=CC=C(C2=NNC(C(NCCCSSCCN)=O)=C2)C=C1

  • Target

    Bcl-2 Family

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature
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CBI1

CBI1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.