Cbl-b-IN-15

Name: Cbl-b-IN-15
Brand: QuantiMol
SKU: QM-0071838-01
Price: 1656.23 GBP
Availability: InStock

Size 1 mg 5 mg 10 mg

SKU:QM-0071838-01

£1,656.23 GBP

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Product Details

Description
Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ligase Cbl (IC50: 15 nM) . Cbl-b refers to Casitas B-lineage lymphoma proto-oncogene-b, which inhibits T-cell, natural killer (NK) cell, and B-cell activation. Cbl-b-IN-15 activates T cell function with EC50=0.41 μM[1].
Molecular Formula
C27H27N5O3
Molecular Weight
469.53
Smiles
O=C1[C@@H](NC(C2=CC=CC=C2CN3CCO[C@@H](C)C3)=O)N=C(C4=CC=CC=C4)C5=CC=NC=C5N1
Target
E1/E2/E3 Enzyme
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0071838-01	1 mgQM-0071838-01 £1,656.23/ea	£0.00	Quantity	£1,656.23/ea	£0.00

5 mgQM-0071838-02	5 mgQM-0071838-02 £4,066.79/ea	£0.00	Quantity	£4,066.79/ea	£0.00

10 mgQM-0071838-03	10 mgQM-0071838-03 £6,075.19/ea	£0.00	Quantity	£6,075.19/ea	£0.00

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Cbl-b-IN-15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.