Cbl-b-IN-16

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SKU:QM-0135677

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Product Details

Description
Cbl-b-IN-16 (compound 31) is an orally active Cbl-b inhibtor with IC50 of 30 nM and induces IL-2 production in Hu-T-cells with EC50 of 230 nM. Cbl-b-IN-16 exhibits antitumor activity[1].
Molecular Formula
C26H27F3N6O
Molecular Weight
496.53
Smiles
O=C1C(C2=CC=CC([C@@]3(C4=NN=CN4C)C[C@H](C)C3)=C2)=CC(C(F)(F)F)=CN1[C@H](C5=CN(C)N=C5)C
Target
E1/E2/E3 Enzyme
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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Cbl-b-IN-16 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.