CCW 28-3 [CAS 2361142-23-4]

CCW 28-3 is a PROTAC-based BRD4 degrader in a proteasome- and RNF4-dependent manner (Pink: JQ-1 (carboxylic acid) ; Black: linker (HY-170384) ; Blue: RNF4 ligand CCW16 (HY-143346) ).

[2361142-23-4]

C44H42Cl2N6O4S

821.81

O=C(CCl)N(C1=CC=C(C=C1)OC2=CC=C(C=C2)OCCCCNC(C[C@H]3C4=NN=C(N4C5=C(C(C6=CC=C(C=C6)Cl)=N3)C(C)=C(S5)C)C)=O)CC7=CC=CC=C7

Epigenetic Reader Domain; PROTACs

Room temperature