CD73-IN-7 [CAS 2763709-14-2]

CD73-IN-7 is a potent inhibitor of CD73. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP), and adenosine can induce immunosuppressive effects and promote tumor proliferation and/or metastasis. CD73-IN-7 be used for preparing a medicament for tumor-related diseases (extracted from patent WO2022052886A1, compound 13) [1].

[2763709-14-2]

C13H11ClN4O2

290.71

C=C[C@H]1C[C@@H]1C2=CC(C3=CNC(NC3=O)=O)=NN=C2Cl

CD73

10 mM in DMSO

Room temperature