Cefetamet (sodium) [CAS 65243-25-6]

Cefetamet (Ro 15-8074) sodium is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil. Cefetamet sodium binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet sodium has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet sodium kills and lyses Treponema pallidum. Cefetamet sodium can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis[1][2][3][4][5].

[65243-25-6]

C14H14N5NaO5S2

419.41

O=C(O[Na])C(N1[C@@]([H])([C@@H](C1=O)NC(/C(C2=CSC(N)=N2)=N\OC)=O)SC3)=C3C

Antibiotic; Bacterial; Drug Metabolite; Penicillin-binding protein (PBP)

10 mM in DMSO

Room temperature