Ceftiofur (sodium) [CAS 104010-37-9]

Ceftiofur sodium is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur sodium exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur sodium also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6[1][2][3].

[104010-37-9]

C19H16N5NaO7S3

545.54

O=C(O[Na])C(N12)=C(CSC(C3=CC=CO3)=O)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O

Antibiotic; Bacterial; Interleukin Related; NF-κB; p38 MAPK; TNF Receptor

β-lactam

10mM

98.03

DMSO : 50 mg/mL (ultrasonic)

4°C (Powder, sealed storage, away from moisture)

Room Temperature

H317, H334

H317, H334