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Celastramycin A (isomer) [CAS 491600-94-3]
Celastramycin A (isomer) [CAS 491600-94-3]
SKU:QM-0109837-01
£381.69 GBP
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Product Details
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Description
Celastramycin A isomer is an isomer of Celastramycin A , an antibiotic against Gram-negative bacteria and Mycobacterium tuberculosis with an MIC of 0.05-3.1 μg/mL. Celastramycin A exerts immunosuppressive effects in Drosophila ex vivo via the immunodeficiency pathway (IC50 of 8 ng/mL), inhibits human innate immune responses via the TNF-α pathway, and inhibits IL-8 production in HUEVC with an IC50 of 60 ng/mL[1][2].
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CAS Number
[491600-94-3]
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Molecular Formula
C17H18Cl3NO3
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Molecular Weight
390.69
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Smiles
O=C(C1=C(O)C(CCCCCC)=CC(Cl)=C1O)C2=CNC(Cl)=C2Cl
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Target
Antibiotic; Bacterial
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Shipping Conditions
Room temperature
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Celastramycin A (isomer) [CAS 491600-94-3]
Celastramycin A (isomer) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.