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SKU:QM-0148347-01
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Cemsidomide (CFT7455) is a ubiquitin ligase pathway based IKZF1/3 (Ikaros/Aiolos) degrader with molecular glue activity[1]. Cemsidomide has a GI50 of 0.05 nM for NCIH929.1 cells. Cemsidomide is used in the research of multiple myeloma (MM) [1][2].
[2504235-67-8]
C28H27N3O4
469.53
O=C1N([C@]2([H])C(NC(CC2)=O)=O)C3=CC=C(C4=CC=CC1=C43)CC5=CC=C(C=C5)CN6CCOCC6
IKZF Family; Molecular Glues
Cereblon; IKZF1; IKZF3
10mM
99.54
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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Cemsidomide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.