Centmitor-1 [CAS 331749-88-3]

Centmitor-1 (Cent-1) is a mitotic arrest inducer. Centmitor-1 modulates microtubule plus-ends and reduced microtubule dynamics. In cells, Centmitor-1 causes mitotic arrest characterized by chromosome alignment defects, multipolar spindles, centrosome fragmentation, and activated spindle assembly checkpoint[1].

[331749-88-3]

C22H16BrN3O3

450.28

O=C1C2=C(N(CC(N/N=C/C3=CC=C(C(Br)=C3)O)=O)C4=C1C=CC=C4)C=CC=C2

Microtubule/Tubulin

Room temperature

H302-H410

P264-P270-P273-P330-P391-P501