Cephalochromin [CAS 25908-26-3]

Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI) . Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC50 of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL[1].

[25908-26-3]

C28H22O10

518.47

OC(C(C(C=C1O[C@@H](C2)C)=[C@@](C(O)=C3)[C@@](C(O)=C4)=C(C=C5O[C@@H](C6)C)C(C(O)=C5C6=O)=C4O)=C3O)=C1C2=O

Antibiotic; Bacterial

Room temperature