Name: Cevidoplenib [CAS 1703788-21-9]
Brand: QuantiMol
SKU: QM-0136396-01
Price: 288.14 GBP
Availability: InStock

Product Details

Description
Cevidoplenib (SKI-O-703) is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SKI-O-592. Cevidoplenib and SKI-O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SKI-O-592 potently inhibits multiple kinases with IC50s of 6.2 nM (Syk), 1.859 μM (Jak2), 5.807 μM (Jak3), 0.412 μM (RET), 0.687 μM (KOR), 1.783 μM (FLT3), 16.96 μM (FGFR1), 5.662 μM (FGFR3), and 0.709 μM (Pyk2), respectively[1][2][3].
CAS Number
[1703788-21-9]
Molecular Formula
C25H27N7O3
Molecular Weight
473.53
Smiles
O=C(C1CC1)C2=CN(C)C3=C2C=C(NC4=NC=CC(N5N=C(C)C(CN6OC[C@@H](O)C6)=C5)=N4)C=C3
Target
Syk
Purity
99.58
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0136396-01	5 mgQM-0136396-01 £288.14/ea	£0.00	Quantity	£288.14/ea	£0.00

10 mM - 1 mLQM-0136396-02	10 mM - 1 mLQM-0136396-02 £299.07/ea	£0.00	Quantity	£299.07/ea	£0.00

10 mgQM-0136396-03	10 mgQM-0136396-03 £351.32/ea	£0.00	Quantity	£351.32/ea	£0.00

25 mgQM-0136396-04	25 mgQM-0136396-04 £664.79/ea	£0.00	Quantity	£664.79/ea	£0.00

50 mgQM-0136396-05	50 mgQM-0136396-05 £991.63/ea	£0.00	Quantity	£991.63/ea	£0.00

100 mgQM-0136396-06	100 mgQM-0136396-06 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

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Cevidoplenib [CAS 1703788-21-9]

Cevidoplenib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.