CFTR corrector 4 [CAS 1918142-34-3]

CFTR corrector 4 (Compound 13), an active (R, R) -form enantiomer, is a highly potent and orally active cystic fibrosis transmembrane conductance regulator (CFTR) corrector. CFTR corrector 4 can increase CFTR levels at the cell surface and have the potential for treatment of cystic fibrosis[1].

[1918142-34-3]

C29H27F2NO7

539.52

O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)N[C@@H]4C[C@H](C5=CC=C(OC)C(OC)=C5)OC6=CC(OC)=CC=C46

CFTR

99.72

DMSO : 110 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature